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A5427012

Myricetin , 97% , 529-44-2

Synonym(s):
3,3ʹ,4ʹ,5,5ʹ,7-Hexahydroxyflavone, Hsp70 Inhibitor II;3,3′,4′,5,5′,7-Hexahydroxyflavone;Cannabiscetin;Myricetin - CAS 529-44-2 - Calbiochem;Myricetol

CAS NO.:529-44-2

Empirical Formula: C15H10O8

Molecular Weight: 318.24

MDL number: MFCD00006827

EINECS: 208-463-2

Pack Size Price Stock Quantity
25MG RMB31.20 In Stock
100MG RMB69.60 In Stock
500MG RMB164.00 In Stock
5G RMB736.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >300 °C(lit.)
Boiling point: 377.41°C (rough estimate)
Density  1.4222 (rough estimate)
refractive index  1.4395 (estimate)
storage temp.  2-8°C
solubility  ethanol: soluble10mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow
pka 6.30±0.40(Predicted)
form  crystalline
color  Yellowish Brown
Water Solubility  Soluble in dimethyl sulfoxide,dimethyl formamide and ethanol. Insoluble in water.
Merck  14,6332
BRN  332331
Stability: Hygroscopic
InChIKey IKMDFBPHZNJCSN-UHFFFAOYSA-N
LogP 1.206 (est)
CAS DataBase Reference 529-44-2(CAS DataBase Reference)

Description and Uses

Myricetin[529-44-2] is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant. Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 μM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.

Myricetin is used as an antioxidant. It is a cell-permeable flavonoid used in inflammatory, diabetes, and cancer studies. It is effective in protecting neurons against oxidative stresses. Further, it inhibits yeast alfa-glucosidase,1 glyoxalase I in vitro and bovine milk xanthine oxidase.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  LK8646000
10
HS Code  29329990
Hazardous Substances Data 529-44-2(Hazardous Substances Data)

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