Home Categories Chemical Reagents Methylglyoxal
A5411112

Methylglyoxal , 32%solution , 78-98-8

Synonym(s):
Acetylformaldehyde;Methylglyoxal solution;Pyruvaldehyde;Pyruvic aldehyde

CAS NO.:78-98-8

Empirical Formula: C3H4O2

Molecular Weight: 72.06

MDL number: MFCD00006960

EINECS: 201-164-8

Pack Size Price Stock Quantity
250G RMB92.00 In Stock
1KG RMB306.40 In Stock
5kg RMB1258.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 25 °C
Boiling point: 72 °C
Density  1.19 g/mL at 20 °C
vapor pressure  25.09hPa at 20℃
refractive index  n20/D 1.4209
RTECS  UZ0700000
FEMA  2969 | PYRUVALDEHYDE
storage temp.  2-8°C
solubility  DMSO (Slightly), Methanol (Slightly), Water (Soluble)
form  Solution
color  Clear yellow to yellow-brown
Odor at 1.00 % in propylene glycol. sweet acidic ethereal brown rum
Odor Type caramellic
Water Solubility  >=10 g/100 mL at 17 ºC
Sensitive  Air Sensitive
Merck  14,6081
JECFA Number 937
BRN  906750
InChIKey AIJULSRZWUXGPQ-UHFFFAOYSA-N
LogP -1.06 at 25℃

Description and Uses

Methylglyoxal (MG) is a highly reactive a-dicarbonyl compound that is primarily generated endogenously during glycolytic pathways (glucose and fructose metabolism) in cells and exogenously due to autoxidation of sugar, degradation of lipids, and fermentation during food and drink processing. Methylglyoxal polymerizes readily; it is hygroscopic and incompatible with strong oxidizing agents and bases. Methylglyoxal may be present as a free molecule in the diet or bound to biological materials, such as proteins, and as advanced glycation end products (AGEs), which are poorly absorbed. Methylglyoxal has been indicated in pathological events associated with hyperglycemia in both type 1 and type 2 diabetes and in other diabetic complications as either a direct toxin or as a precursor for AGEs. In animal studies, MG has been shown to induce tumorigenesis, but has also been reported as a tumoristatic agent. Methylglyoxal has been identified as the dominant antibacterial constituent of manuka honey.

Used in organic synthesis, as a flavoring agent, and in tanning leather. Commercial formulation is available as a 30% aqueous solution. No safety concern at current levels of intake when used as a flavoring agent.

Safety

Symbol(GHS) 
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H290-H317-H318-H341
Precautionary statements  P202-P234-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xn,Xi,C
Risk Statements  22-36-35
Safety Statements  26-36-45-36/37/39
RIDADR  UN 3265 8 / PGIII
WGK Germany  -
Hazard Note  Irritant
TSCA  Yes
HS Code  29121900

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