(1R,2S,5R)-(-)-Menthol , 99.5% , 2216-51-5

Synonym(s):
(-)-Menthol;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol;2-Isopropyl-5-methylcyclohexanol;(?)-Menthol;(1R,2S,5R)-(?)-Menthol

CAS NO.：2216-51-5

Empirical Formula: C10H20O

Molecular Weight: 156.27

MDL number: MFCD00062979

EINECS: 218-690-9

PRODUCT Properties

• Melting point: 41-45 °C (lit.)
• Boiling point: 212 °C (lit.)
• alpha: -51 º (589nm, c=10, EtOH)
• Density: 0.89 g/mL at 25 °C (lit.)
• vapor pressure: 0.8 mm Hg ( 20 °C)
• FEMA: 2665 | MENTHOL RACEMIC
• refractive index: 1.46
• Flash point: 200 °F
• storage temp.: Store below +30°C.
• solubility: 490mg/l
• form: Crystals or Crystalline Needles
• pka: 15.30±0.60(Predicted)
• color: Colorless to white
• Specific Gravity: 0.89
• Odor: at 10.00 % in dipropylene glycol. peppermint cooling mentholic minty
• Odor Type: mentholic
• optical activity: [α]22/D 49°, c = 10 in 95% ethanol
• Water Solubility: insoluble
• Merck: 14,5837
• BRN: 1902293
• Dielectric constant: 3.2（Ambient）
• Stability: Stable.
• InChIKey: NOOLISFMXDJSKH-KXUCPTDWSA-N
• LogP: 3.15 at 25℃

Description and Uses

L-Menthol is used as a cooling agent that strongly activates TRPM8.(Transient Receptor Potential Cation Channel, Subfamily M, Member 8 is a Protein Coding gene). It is used as analgesic (topical), antipruritic agent. It is used as: refreshing agent, food flavor, cool and antipruritic drug, carminative drug. Menthol crystals is used for pers onal care and cosmetics.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• Hazard Codes: Xi
• Risk Statements: 37/38-41-36/37/38
• Safety Statements: 26-39-37/39-36
• WGK Germany: 2
• RTECS: OT0700000
• TSCA: Yes
• HS Code: 29061100
• Toxicity: LD50 orally in Rabbit: 3300 mg/kg LD50 dermal Rabbit > 5000 mg/kg