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A5363812

Methylene blue stain for DNA , 100XDNASTAIN , 7220-79-3

Synonym(s):
Methylene blue;Methylthioninium chloride;Methylene Blue trihydrate;Methylene Blue hydrate;Methylthionini chloridum

CAS NO.:7220-79-3

Empirical Formula: C16H24ClN3O3S

Molecular Weight: 373.9

MDL number: MFCD00150008

EINECS: 615-731-6

Pack Size Price Stock Quantity
25ML RMB295.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 190 °C (dec.)(lit.)
Density  0.98 g/mL at 25 °C
Flash point: 14 °C
storage temp.  no restrictions.
solubility  Soluble in water, chloroform; sparingly soluble in ethanol
Colour Index  52015
form  Solid
pka 2.6, 11.2(at 25℃)
color  Green
Water Solubility  4 g/100 mL
λmax 668 nm, 609 nm
Merck  13,6085
Stability: Stable. Incompatible with bases, reducing agents, strong oxidizing agents.
Biological Applications Diagnosis of tauopathy,Alzheimer’s disease (AD),Pick’s disease; treating prophylaxis; dental materials
InChIKey YAFGUSOAMIMROI-UHFFFAOYSA-M
CAS DataBase Reference 7220-79-3(CAS DataBase Reference)
IARC 3 (Vol. 108) 2016
EPA Substance Registry System Methylene blue trihydrate (7220-79-3)

Description and Uses

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn,F
Risk Statements  22-36/37/38-11
Safety Statements  26-36-24/25-16-7
RIDADR  UN 1170 3/PG 2
WGK Germany  3
RTECS  SP5740000
TSCA  Yes
HS Code  32129000

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