(±)-Miconazole nitrate salt , 98% , 22832-87-7
Synonym(s):
(±)-Miconazole nitrate salt;1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole
CAS NO.:22832-87-7
Empirical Formula: C18H15Cl4N3O4
Molecular Weight: 479.14
MDL number: MFCD00058161
EINECS: 245-256-6
Pack Size | Price | Stock | Quantity |
1G | RMB41.60 | In Stock |
|
5G | RMB102.40 | In Stock |
|
25G | RMB295.20 | In Stock |
|
100g | RMB767.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 170-185 C |
Density | 1.5000 (rough estimate) |
refractive index | 1.6200 (estimate) |
storage temp. | 2-8°C |
solubility | pyridine: soluble50mg/mL |
form | Solid |
color | white to off-white |
optical activity | [α]25/D 0°, c = 10 in water |
Water Solubility | Slightly soluble in water. Soluble in propylene glycol or pyridine. |
Merck | 14,6178 |
InChIKey | MCCACAIVAXEFAL-UHFFFAOYSA-N |
CAS DataBase Reference | 22832-87-7(CAS DataBase Reference) |
Description and Uses
Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-
Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.