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A5357712

(±)-Miconazole nitrate salt , 98% , 22832-87-7

Synonym(s):
(±)-Miconazole nitrate salt;1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole

CAS NO.:22832-87-7

Empirical Formula: C18H15Cl4N3O4

Molecular Weight: 479.14

MDL number: MFCD00058161

EINECS: 245-256-6

Pack Size Price Stock Quantity
1G RMB41.60 In Stock
5G RMB102.40 In Stock
25G RMB295.20 In Stock
100g RMB767.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 170-185 C
Density  1.5000 (rough estimate)
refractive index  1.6200 (estimate)
storage temp.  2-8°C
solubility  pyridine: soluble50mg/mL
form  Solid
color  white to off-white
optical activity [α]25/D 0°, c = 10 in water
Water Solubility  Slightly soluble in water. Soluble in propylene glycol or pyridine.
Merck  14,6178
InChIKey MCCACAIVAXEFAL-UHFFFAOYSA-N

Description and Uses

Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.

Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-43-40
Safety Statements  36/37
RIDADR  3249
WGK Germany  3
RTECS  NI4771000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933290000

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