Myristyltrimethylammonium bromide , Ion to chromatography, ≥99.0%(AT) , 1119-97-7
Synonym(s):
Tetradecyl trimethyl ammonium Bromide, Myr istyl tri methyl ammonium Bromide, TTAB;Dynamin Inhibitor II, MiTMAB - CAS 1119-97-7 - Calbiochem;Myristyltrimethylammonium bromide;Tetradecyltrimethylammonium bromide;Trimethyl(tetradecyl)ammonium bromide
CAS NO.：1119-97-7
Empirical Formula: C17H38BrN
Molecular Weight: 336.39
MDL number: MFCD00011770
EINECS: 214-291-9
| Pack Size | Price | Stock | Quantity |
| 10G | RMB215.20 | In Stock |
|
| 50G | RMB788.80 | In Stock |
|
| 100G | RMB1536.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 245-250 °C(lit.) |
| Density | 1.1328 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5260 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | H2O: 10 % (w/v) |
| form | Fine Crystalline Powder |
| color | White |
| PH | pH (50g/l, 25℃ : 4.0～6.0 |
| Water Solubility | 20 g/100 mL |
| Sensitive | Hygroscopic |
| λmax | λ: 240 nm Amax: ≤0.08 λ: 250 nm Amax: ≤0.05 λ: 260 nm Amax: ≤0.04 λ: 500 nm Amax: ≤0.02 |
| Merck | 14,6336 |
| BRN | 3633227 |
| Stability: | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| InChIKey | CXRFDZFCGOPDTD-UHFFFAOYSA-M |
| LogP | 2.2 at 20℃ |
Description and Uses
MiTMAB (1119-97-7) is a dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940nM.1 Rapidly and reversibly inhibits multiple forms of endocytosis with no acute cellular damage1. A useful pharmacological tool for studying dynamin-mediated trafficking events.2 Induces cytokinesis failure and apoptosis in human cancer cells.3 Induces cytoprotective autophagy in human Jurkat T cells.4
Myristyltrimethylammonium has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.??It has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.
Safety
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H335-H373-H400 |
| Precautionary statements | P273-P280-P301+P312-P302+P352-P305+P351+P338-P314 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45-27 |
| RIDADR | UN 3263 8/PG 2 |
| WGK Germany | 3 |
| RTECS | BS5776000 |
| F | 3 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29239000 |
| Toxicity | LD50 in mice, rats (mg/kg): 12.0, 15.0 i.v. (Issomaa, Bjondahl) |
