A5294812
Lacidipine , ≥98% , 103890-78-4
Synonym(s):
3,5-Diethyl 4-{2-[(1E)-3-(tert-butoxy)-3-oxoprop-1-en-1-yl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;4-[2-[(1E)-3-(1,1-Dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-diethyl ester;CID 5311217;GR-43659X;GX-1048
CAS NO.：103890-78-4
Empirical Formula: C26H33NO6
Molecular Weight: 455.54
MDL number: MFCD00865936
EINECS: 638-759-0
| Pack Size | Price | Stock | Quantity |
| 50MG | RMB31.20 | In Stock |
|
| 250MG | RMB35.20 | In Stock |
|
| 1G | RMB83.20 | In Stock |
|
| 200mg | RMB632.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 174-175°C |
| Boiling point: | 558.4±50.0 °C(Predicted) |
| Density | 1.127±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL, clear |
| pka | 3.00±0.70(Predicted) |
| form | powder |
| color | white to beige |
| Merck | 14,5331 |
| InChIKey | GKQPCPXONLDCMU-CCEZHUSRSA-N |
Description and Uses
Lacidipine is a new second-generation dihydropyridine calcium antagonist introduced as a once a day treatment for mild to moderate hypertension. It is reported to have high selectivity for vascular smooth muscle and also a long duration of action. The use of lacidipine as an antiatherosclerotic agent is currently under investigation.
A dihydropyridine calcium channel blocker. Antihypertensive.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312+P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| RTECS | US7970200 |
| Toxicity | mouse,LD50,intraperitoneal,80200ug/kg (80.2mg/kg),SKIN AND APPENDAGES (SKIN): HAIR: OTHERSENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYEBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 335, 1994. |
