LY294002 , ≥98% , 154447-36-6

Synonym(s):
2-(4-Morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one hydrochloride;2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, BRD2 Inhibitor IV, BRD3 Inhibitor III, BRD4 Inhibitor IV;PI3K inhibitor

CAS NO.：154447-36-6

Empirical Formula: C19H17NO3

Molecular Weight: 307.34

MDL number: MFCD01530034

EINECS: 1312995-182-4

PRODUCT Properties

• Melting point: 183-185℃
• Boiling point: 494.6±45.0 °C(Predicted)
• Density: 1.266
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: DMSO: >5 mg/mL
• form: solid
• pka: 0.55±0.20(Predicted)
• color: white to off-white
• Water Solubility: Soluble in DMSO at 5mg/ml. Insoluble in water
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
• InChIKey: CZQHHVNHHHRRDU-UHFFFAOYSA-N
• CAS DataBase Reference: 154447-36-6

Description and Uses

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor with a 2.7-fold greater potency than quercetin. LY294002 inhibits purified PI3K with an IC₅₀ of 1.4 μM.

LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H320-H361-H370-H372-H336-H402
• Precautionary statements: P501-P273-P260-P270-P202-P201-P271-P264-P280-P337+P313-P305+P351+P338-P308+P311-P301+P312+P330-P304+P340+P312-P403+P233-P405
• Safety Statements: 24-25
• WGK Germany: 3
• HS Code: 29349990