A5285912
Lomustine , 98% , 13010-47-4
Synonym(s):
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea;Lomustine
CAS NO.：13010-47-4
Empirical Formula: C9H16ClN3O2
Molecular Weight: 233.7
MDL number: MFCD00012392
EINECS: 235-859-2
| Pack Size | Price | Stock | Quantity |
| 50mg | RMB144.80 | In Stock |
|
| 250MG | RMB395.20 | In Stock |
|
| 200mg | RMB496.00 | In Stock |
|
| 1G | RMB1216.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 88-90 |
| Boiling point: | 63.6°C (rough estimate) |
| Density | 1.3840 (rough estimate) |
| refractive index | 1.5790 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, soluble in ethanol (96 per cent). |
| form | Solid |
| pka | 10.88±0.20(Predicted) |
| color | Light orange to Yellow to Green |
| Merck | 14,5564 |
| InChIKey | GQYIWUVLTXOXAJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 13010-47-4(CAS DataBase Reference) |
| IARC | 2A (Vol. 26, Sup 7) 1987 |
| EPA Substance Registry System | 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (13010-47-4) |
Description and Uses
Lomustine is a pale yellow powder. Molecularweight = 233.73; Freezing/Melting point = 90℃. Insolublein water.
Chloroethylnitrosourea derivative with antitumor activity. Similar to carmustine, chlorozotocin, nimustine, ranimustine. Antineoplastic.
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H350 |
| Precautionary statements | P201-P280-P301+P330+P331+P310-P308+P313 |
| Hazard Codes | T |
| Risk Statements | 45-25 |
| Safety Statements | 53-45 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | YS4900000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 29299090 |
| Hazardous Substances Data | 13010-47-4(Hazardous Substances Data) |
| Toxicity | LD50 in male mice (mg/kg): 51 orally; 56 i.p.; 61 s.c. (Thompson, Larson) |
