L-Leucine , 99% , 61-90-5

Synonym(s):
(S)-2-Amino-4-methylpentanoic acid;(S)-(+)-Leucine;Leu;L-Leucine;L-Leucine - CAS 61-90-5 - Calbiochem

CAS NO.：61-90-5

Empirical Formula: C6H13NO2

Molecular Weight: 131.17

MDL number: MFCD00002617

EINECS: 200-522-0

PRODUCT Properties

• Melting point: >300 °C (lit.)
• alpha: 15.4 º (c=4, 6N HCl)
• Boiling point: 122-134 °C(Press: 2-3 Torr)
• Density: 1,293 g/cm³
• vapor pressure: <1 hPa (20 °C)
• refractive index: 1.4630 (estimate)
• FEMA: 3297 | L-LEUCINE
• Flash point: 145-148°C
• storage temp.: 2-8°C
• solubility: 1 M HCl: 50 mg/mL
• form: powder
• pka: 2.328(at 25℃)
• color: White to Off-white
• PH: 5.5-6.5 (20g/l, H2O, 20℃)
• Odor: at 100.00?%. odorless
• optical activity: [α]20/D +15.5°, c = 2 in 6 M HCl
• Water Solubility: 22.4 g/L (20 C)
• λmax: λ: 260 nm Amax: 0.05; λ: 280 nm Amax: 0.05
• JECFA Number: 1423
• Merck: 14,5451
• Sublimation: 145-148 ºC
• BRN: 1721722
• Stability: Stability Moisture and light sensitive. Incompatible with strong oxidising agents.
• LogP: 0.80

Description and Uses

Small, white, lustrous plates, or a white, crystalline powder, with a slightly bitter taste. One g dissolves in about 40 mL of water and in about 100 mL of acetic acid. It is sparingly soluble in alcohol, but is soluble in dilute hydrochloric acid and in solutions of alkali hydroxides and carbonates. ι-Leucine may be synthesized by bromination, followed by amination of isocaproic acid; via the acetamidomalonic ester; by isolation from gluten, casein, keratin; from hydantoin.

L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P271-P280
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: OH2850000
• TSCA: Yes
• HS Code: 29224995