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A5253612

L-Leucine , 99% , 61-90-5

Synonym(s):
(S)-2-Amino-4-methylpentanoic acid;(S)-(+)-Leucine;Leu;L-Leucine;L-Leucine - CAS 61-90-5 - Calbiochem

CAS NO.:61-90-5

Empirical Formula: C6H13NO2

Molecular Weight: 131.17

MDL number: MFCD00002617

EINECS: 200-522-0

Pack Size Price Stock Quantity
25G RMB24.00 In Stock
100G RMB31.20 In Stock
250G RMB63.20 In Stock
500G RMB126.40 In Stock
2.5KG RMB631.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >300 °C (lit.)
alpha  15.4 º (c=4, 6N HCl)
Boiling point: 122-134 °C(Press: 2-3 Torr)
Density  1,293 g/cm3
vapor pressure  <1 hPa (20 °C)
refractive index  1.4630 (estimate)
FEMA  3297 | L-LEUCINE
Flash point: 145-148°C
storage temp.  2-8°C
solubility  1 M HCl: 50 mg/mL
form  powder
pka 2.328(at 25℃)
color  White to Off-white
PH 5.5-6.5 (20g/l, H2O, 20℃)
Odor at 100.00?%. odorless
optical activity [α]20/D +15.5°, c = 2 in 6 M HCl
Water Solubility  22.4 g/L (20 C)
λmax λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
JECFA Number 1423
Merck  14,5451
Sublimation  145-148 ºC
BRN  1721722
Stability: Stability Moisture and light sensitive. Incompatible with strong oxidising agents.
LogP 0.80
CAS DataBase Reference 61-90-5(CAS DataBase Reference)
NIST Chemistry Reference Leucine(61-90-5)
EPA Substance Registry System L-Leucine (61-90-5)

Description and Uses

Small, white, lustrous plates, or a white, crystalline powder, with a slightly bitter taste. One g dissolves in about 40 mL of water and in about 100 mL of acetic acid. It is sparingly soluble in alcohol, but is soluble in dilute hydrochloric acid and in solutions of alkali hydroxides and carbonates. ι-Leucine may be synthesized by bromination, followed by amination of isocaproic acid; via the acetamidomalonic ester; by isolation from gluten, casein, keratin; from hydantoin.

L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P280
Safety Statements  24/25
WGK Germany  3
RTECS  OH2850000
TSCA  Yes
HS Code  29224995
Hazardous Substances Data 61-90-5(Hazardous Substances Data)

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