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A5240312

Ketoprofen , ≥98%(HPLC) , 22071-15-4

Synonym(s):
2-(3-Benzoylphenyl)propionic acid;Ketoprofen;KP

CAS NO.:22071-15-4

Empirical Formula: C16H14O3

Molecular Weight: 254.29

MDL number: MFCD00055790

EINECS: 244-759-8

Pack Size Price Stock Quantity
5G RMB36.00 In Stock
25G RMB84.00 In Stock
100G RMB295.20 In Stock
250g RMB639.20 In Stock
500G RMB1039.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 93-96°C
Boiling point: 357.5°C (rough estimate)
Density  1.1565 (rough estimate)
refractive index  1.5600 (estimate)
storage temp.  2-8°C
solubility  Slightly soluble in chloroform and methanol.
pka pKa 5.94(MeOH/H2O) (Uncertain)
form  solid
color  White to Off-White
Water Solubility  209mg/L(room temperature)
Merck  14,5305
InChIKey DKYWVDODHFEZIM-UHFFFAOYSA-N
CAS DataBase Reference 22071-15-4(CAS DataBase Reference)
NIST Chemistry Reference Ketoprofen(22071-15-4)
EPA Substance Registry System Benzeneacetic acid, 3-benzoyl-.alpha.-methyl- (22071-15-4)

Description and Uses

Ketoprofen is a chemical that comes in the form of a white crystalline powder; odorless or nearly odorless. It is very soluble in methanol, soluble in ethanol, acetone or ether, and almost insoluble in water. The melting point is about 93-96 °C. For the arylalkanoic acid compounds. Has analgesic, anti-inflammatory and antipyretic effects. The anti-inflammatory effect is stronger than that of ibuprofen, with less side effects and low toxicity. Oral and easily absorbed from the gastrointestinal tract. After 1 administration, the peak plasma concentration can be reached in about 0.5 to 2 hours. t 1/2 is 1.6 to 1.9 hours. In the blood and plasma protein binding force is extremely strong. The excretion rate from urine is 30% to 90% within 24 hours. Mainly excreted in the form of glucuronic acid conjugates. For rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout, etc.

Natural Vitamin B12. analog

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P405-P501
Hazard Codes  T
Risk Statements  25-36/37/38-23/24/25
Safety Statements  26-45-36/37/39
RIDADR  2811
WGK Germany  3
RTECS  UE7570000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29183000
Toxicity LD50 orally in rats: 101 mg/kg (Ueno)

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