Ketoprofen , ≥98%(HPLC) , 22071-15-4
Synonym(s):
2-(3-Benzoylphenyl)propionic acid;Ketoprofen;KP
CAS NO.:22071-15-4
Empirical Formula: C16H14O3
Molecular Weight: 254.29
MDL number: MFCD00055790
EINECS: 244-759-8
Pack Size | Price | Stock | Quantity |
5G | RMB36.00 | In Stock |
|
25G | RMB84.00 | In Stock |
|
100G | RMB295.20 | In Stock |
|
250g | RMB639.20 | In Stock |
|
500G | RMB1039.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 93-96°C |
Boiling point: | 357.5°C (rough estimate) |
Density | 1.1565 (rough estimate) |
refractive index | 1.5600 (estimate) |
storage temp. | 2-8°C |
solubility | Slightly soluble in chloroform and methanol. |
pka | pKa 5.94(MeOH/H2O) (Uncertain) |
form | solid |
color | White to Off-White |
Water Solubility | 209mg/L(room temperature) |
Merck | 14,5305 |
InChIKey | DKYWVDODHFEZIM-UHFFFAOYSA-N |
CAS DataBase Reference | 22071-15-4(CAS DataBase Reference) |
NIST Chemistry Reference | Ketoprofen(22071-15-4) |
EPA Substance Registry System | Benzeneacetic acid, 3-benzoyl-.alpha.-methyl- (22071-15-4) |
Description and Uses
Ketoprofen is a chemical that comes in the form of a white crystalline powder; odorless or nearly odorless. It is very soluble in methanol, soluble in ethanol, acetone or ether, and almost insoluble in water. The melting point is about 93-96 °C. For the arylalkanoic acid compounds. Has analgesic, anti-inflammatory and antipyretic effects. The anti-inflammatory effect is stronger than that of ibuprofen, with less side effects and low toxicity. Oral and easily absorbed from the gastrointestinal tract. After 1 administration, the peak plasma concentration can be reached in about 0.5 to 2 hours. t 1/2 is 1.6 to 1.9 hours. In the blood and plasma protein binding force is extremely strong. The excretion rate from urine is 30% to 90% within 24 hours. Mainly excreted in the form of glucuronic acid conjugates. For rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout, etc.
Natural Vitamin B12. analog
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264-P270-P301+P310-P405-P501 |
Hazard Codes | T |
Risk Statements | 25-36/37/38-23/24/25 |
Safety Statements | 26-45-36/37/39 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | UE7570000 |
TSCA | Yes |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29183000 |
Toxicity | LD50 orally in rats: 101 mg/kg (Ueno) |