Ketorolac tris salt , ≥99% , 74103-07-4

Synonym(s):
(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt;Ketorolac tris salt;Toradol

CAS NO.：74103-07-4

Empirical Formula: C19H24N2O6

Molecular Weight: 376.4

MDL number: MFCD00887595

PRODUCT Properties

• Melting point: 160-161 C
• storage temp.: 2-8°C
• solubility: H₂O: 15 mg/mL stable at least one month at −20 °C., soluble
• form: crystalline
• color: White to Light yellow
• λmax: 322nm(MeOH)(lit.)
• Merck: 14,5306
• Stability: Hygroscopic
• InChI: InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2
• InChIKey: BWHLPLXXIDYSNW-UHFFFAOYSA-N
• SMILES: C(N)(CO)(CO)CO.C(C1C=CC=CC=1)(C1=CC=C2C(C(=O)O)CCN12)=O
• CAS DataBase Reference: 74103-07-4(CAS DataBase Reference)

Description and Uses

Ketorolac tromethamine is a nonsteroidal antiinflammatory agent that exhibits analgesic and antipyretic activity. The compound is effective in the management of moderate to severe postoperative pain. It is, however, the first of this type of agent to be administered parenterally as an analgesic and is specifically indicated for intramuscular injection. Ketorolac represents a useful alternative to the narcotic analgesics due to its lack of abuse potential.

Ketorolac is used primarily for its analgesic effects for short-term treatment of mild to moderate pain in dogs and rodents. The duration of analgesic effect in dogs is about 8 – 12 hours, but because of the availability of approved, safer NSAIDs for dogs, its use is questionable.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H315-H319-H335
• Precautionary statements: P301+P310+P330-P302+P352-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25-36/37/38-23/24/25
• Safety Statements: 26-45-36/37/39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: UY7759900
• HazardClass: 6.1(a)
• PackingGroup: II
• HS Code: 2933995500