Home Categories API Kasugamycin hydrochloride
A5238612

Kasugamycin hydrochloride , ≥90%(HPLC) , 19408-46-9

Synonym(s):
3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D-arabino-hexopyranosyl]-D-chiro-inositol hydrochloride;3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D-arabino-hexopyranosyl]-D-chiro-inositol

CAS NO.:19408-46-9

Empirical Formula: C14H25N3O9.ClH

Molecular Weight: 415.82

MDL number: MFCD00058459

EINECS: 637-144-4

Pack Size Price Stock Quantity
1g RMB319.20 In Stock
5G RMB922.40 In Stock
25g RMB3759.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 202-204 °C (decomp)
vapor pressure  <1.3x l0-8 Pa (25 °C)
storage temp.  Sealed in dry,2-8°C
solubility  H2O: soluble
pka 3.23 (carboxyl), 7.73 and 11.0 (bases)
Water Solubility  125 g l-1 (25 °C)
form  Solid
color  white to off-white
Stability: Hygroscopic

Description and Uses

Kasugamycin is an aminoglycosidic antibiotic isolated from S. kasugaensis. It blocks the initiation of translation, preventing initiation complex formation on 30S ribosomes in bacteria.

kasugamycin, derived from Streptomyces kasuguensis, is also used to control rice blast.It acts by inhibiting protein synthesis by interfering with the binding of aminoacyl-tRNA to the mRNA-30s ribosomal subunit complex (Yamaguchi, 1998).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Safety Statements  22-24/25-26
WGK Germany  2
RTECS  NM7521800

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