A5236112
Kasugamycin hydrochloride , Analysis of standard products, ≥90%(HPLC) , 19408-46-9
Synonym(s):
3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D -arabino-hexopyranosyl]-D -chiro-inositol hydrochloride;3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D -arabino-hexopyranosyl]-D -chiro-inositol
CAS NO.:19408-46-9
Empirical Formula: C14H25N3O9.ClH
Molecular Weight: 415.82
MDL number: MFCD00058459
EINECS: 637-144-4
Pack Size | Price | Stock | Quantity |
250MG | RMB324.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 202-204 °C (decomp) |
vapor pressure | <1.3x l0-8 Pa (25 °C) |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: soluble |
pka | 3.23 (carboxyl), 7.73 and 11.0 (bases) |
Water Solubility | 125 g l-1 (25 °C) |
form | Solid |
color | white to off-white |
Stability: | Hygroscopic |
Description and Uses
Kasugamycin is an aminoglycosidic antibiotic isolated from S. kasugaensis. It blocks the initiation of translation, preventing initiation complex formation on 30S ribosomes in bacteria.
kasugamycin, derived from Streptomyces kasuguensis, is also used to control rice blast.It acts by inhibiting protein synthesis by interfering with the binding of aminoacyl-tRNA to the mRNA-30s ribosomal subunit complex (Yamaguchi, 1998).
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H320-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Safety Statements | 22-24/25-26 |
WGK Germany | 2 |
RTECS | NM7521800 |