A5069912
Isobutyric anhydride , >95.0%(GC) , 97-72-3
Synonym(s):
2-Methylpropionic anhydride;Bis(2-methylpropionic acid) anhydride, 2-Methylpropionic anhydride;Isobutyric anhydride
CAS NO.：97-72-3
Empirical Formula: C8H14O3
Molecular Weight: 158.2
MDL number: MFCD00008913
EINECS: 202-603-6
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | -56 °C (lit.) |
| Boiling point: | 182 °C (lit.) |
| Density | 0.954 g/mL at 25 °C (lit.) |
| vapor density | 5.45 (vs air) |
| vapor pressure | 10 mm Hg ( 67 °C) |
| refractive index | n |
| Flash point: | 152 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| color | Clear colorless |
| explosive limit | 1.09%, 87°F |
| Water Solubility | decomposes |
| Sensitive | Moisture Sensitive |
| BRN | 386267 |
| Exposure limits | ACGIH: TWA 10 ppm NIOSH: TWA 10 ppm(30 mg/m3); STEL 15 ppm(45 mg/m3) |
| Dielectric constant | 13.9（20℃） |
| LogP | 1.1 at 25℃ |
| CAS DataBase Reference | 97-72-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 2-methyl-, anhydride(97-72-3) |
| EPA Substance Registry System | Isobutyric anhydride (97-72-3) |
Description and Uses
Isobutyric anhydride was used in the synthesis of 4-O-isobutyryl derivative via reaction with octyl β-D-glucopyranoside in the presence of C2-symmetric chiral 4-pyrrolidinopyridine as a catalyst.
Safety
| Symbol(GHS) |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H301+H311-H314 |
| Precautionary statements | P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P361+P364 |
| Hazard Codes | C |
| Risk Statements | 34-21/22 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | 2922 |
| WGK Germany | 3 |
| RTECS | NQ5550000 |
| F | 13-21 |
| Autoignition Temperature | 624 °F |
| TSCA | Yes |
| HS Code | 2915 90 70 |
| HazardClass | 8 |
| PackingGroup | II |
| Hazardous Substances Data | 97-72-3(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 266 mg/kg LD50 dermal Rabbit 475 mg/kg |
