Home Categories Biochemical Engineering <i>N</i>-(<i>tert</i>-Butoxycarbonyl)-5-aminovaleric Acid
A5055512

<i>N</i>-(<i>tert</i>-Butoxycarbonyl)-5-aminovaleric Acid , ≥98.0%(GC) , 27219-07-4

Synonym(s):
5-(Boc-amino)pentanoic acid;5-(Boc-amino)valeric acid

CAS NO.:27219-07-4

Empirical Formula: C10H19NO4

Molecular Weight: 217.26

MDL number: MFCD00076903

Pack Size Price Stock Quantity
1g RMB56.80 In Stock
5G RMB197.60 In Stock
25G RMB655.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 48-52 °C(lit.)
Boiling point: 160-168 °C0.8 mm Hg(lit.)
Density  1.1518 (rough estimate)
refractive index  1.4500 (estimate)
Flash point: >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  soluble in Methanol
form  Powder
pka 4.72±0.10(Predicted)
color  Off-white
BRN  2048862
CAS DataBase Reference 27219-07-4(CAS DataBase Reference)

Description and Uses

Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Boc-5-aminovaleric acid can be used to synthesize inhibitors of bacterial quorum seining and biofilm formation. It can also be used to synthesize diblock and triblock copolymers.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10-21
HazardClass  IRRITANT
HS Code  29241990

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