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A5040312

Isoprenaline HCl , ≥99% , 51-30-9

Synonym(s):
(±)-Isoproterenol hydrochloride;N-Isopropyl-DL-noradrenaline hydrochloride;1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;Isoprenaline hydrochloride;Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem

CAS NO.:51-30-9

Empirical Formula: C11H18ClNO3

Molecular Weight: 247.72

MDL number: MFCD00012603

EINECS: 200-089-8

Pack Size Price Stock Quantity
1G RMB65.60 In Stock
5G RMB127.20 In Stock
25G RMB508.00 In Stock
100G RMB1836.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 165-175 °C (dec.)(lit.)
Boiling point: 192°C (rough estimate)
Density  1.2296 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  2-8°C
solubility  Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
form  White solid
color  White to Off-White
Water Solubility  Soluble
BRN  3917363
Stability: Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents.
InChI InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChIKey IROWCYIEJAOFOW-UHFFFAOYSA-N
SMILES C1(=CC=C(O)C(O)=C1)C(O)CNC(C)C.Cl

Description and Uses

Isoprenaline hydrochloride is an FDA-approved injectable drug that is the hydrochloride form of isoprenaline and is used as a bronchodilator, adrenergic beta agonist, cardiotonic, and sympathomimetic. Selective beta-adrenergic agonist that increases cytoplasmic cAMP. promotes glycogenolysis and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit tracheal cells via nitric oxide production. In addition, it can be used as an inducer in an experimental rat model of induced myocardial infarction[1].

Isoproterenol hydrochloride is used as a selective β-adrenergic agonist, increases cytosolic cAMP.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DO1925000
3-8-10
HS Code  29225090
Toxicity LD50 oral in rabbit: 3070mg/kg

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