5-Iodouracil , 99% , 696-07-1

Synonym(s):
2,4-Dihydroxy-5-iodopyrimidine

CAS NO.：696-07-1

Empirical Formula: C4H3IN2O2

Molecular Weight: 237.98

MDL number: MFCD00006020

EINECS: 211-788-2

PRODUCT Properties

• Melting point: 274-276 °C (dec.) (lit.)
• Density: 2.2076 (estimate)
• storage temp.: 2-8°C
• solubility: Very faint turbidity in NH3aq. Soluble in 1M NaOH.
• pka: 7.02±0.10(Predicted)
• form: Fluffy Powder
• color: White to light yellow
• Water Solubility: SOLUBLE IN COLD WATER
• Sensitive: Light Sensitive
• BRN: 4891
• CAS DataBase Reference: 696-07-1(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Iodouracil(696-07-1)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 5-iodo- (696-07-1)

Description and Uses

5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
• Hazard Codes: T,Xi
• Risk Statements: 46-20/21/22-36/37/38
• Safety Statements: 53-22-26-36/37/39-45
• RIDADR: 2811
• WGK Germany: 3
• RTECS: YR0525000
• Hazard Note: Irritant/Carcinogenic/Light Sensitive
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29335990