Home Categories Isoxazole-5-carboxylic acid
A5020312

Isoxazole-5-carboxylic acid , 98% , 21169-71-1

CAS NO.:21169-71-1

Empirical Formula: C4H3NO3

Molecular Weight: 113.07

MDL number: MFCD00156151

Pack Size Price Stock Quantity
1G RMB68.00 In Stock
5G RMB249.60 In Stock
25G RMB925.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 144-148 °C(lit.)
Boiling point: 211.74°C (rough estimate)
Density  1.5808 (rough estimate)
refractive index  1.4543 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Powder
pka 2.29±0.10(Predicted)
color  Slightly yellow
Water Solubility  Slightly soluble in water.
Sensitive  Moisture Sensitive
InChIKey MIIQJAUWHSUTIT-UHFFFAOYSA-N
CAS DataBase Reference 21169-71-1(CAS DataBase Reference)

Description and Uses

Reaction conditions were found to allow the exclusive formation of isoxazole-5-carboxylic acid derivatives by conjugate addition, in acidic medium, of hydroxylamine to β-alkoxyvinyl trichloromethyl ketone in synthesis and reactivity of isoxazoles. Isoxazole-5-carboxylic acid participates in the Synthesis and evaluation of acylguanidine FXa inhibitors. 1, 1, 1-trichloro-4-methoxy-3-penten-2-one postulated in the preparation of isoxazole-5-carboxylic acid from trichloroacetyl chloride, ethyl vinyl ether and hydroxylamine is developed in a fully saturated nitrogen atom theerefore there is no possibility of conjugation with 4- substituents.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-25-24-36-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29349990

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