Home Categories Biochemical Engineering Isorhamnetin
A4997412

Isorhamnetin , >98%(HPLC) , 480-19-3

Synonym(s):
3′-Methoxy-3,4′,5,7-tetrahydroxyflavone;3′-Methylquercetin;3,4′,5,7-Tetrahydroxy 3′-methoxyflavone;Isorhamnetol;Quercetin 3′-methyl ether

CAS NO.:480-19-3

Empirical Formula: C16H12O7

Molecular Weight: 316.26

MDL number: MFCD00017310

EINECS: 207-545-5

Pack Size Price Stock Quantity
50MG RMB681.60 In Stock
250mg RMB1573.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 307°C
Boiling point: 599.4±50.0 °C(Predicted)
Density  1.634±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMF: 10 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka 6.31±0.40(Predicted)
form  Solid
color  Light yellow to Amber to Dark green
BRN  44723
Stability: Hygroscopic
InChIKey IZQSVPBOUDKVDZ-UHFFFAOYSA-N
LogP 1.760 (est)

Description and Uses

Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin . It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 μM). Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 μM), which has an important role in the excretion of xenobiotics at the kidney and liver. It has also been reported to potentiate the neurological actions of nerve growth factor, diminish the cardiotoxic impact of doxorubicin, and have beneficial anti-cancer effects.

Safety

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P281-P280
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-40
Safety Statements  22-36-26-36/37
WGK Germany  3
RTECS  LK9275450
HS Code  29329990

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