A4992812
Isopropyl isocyanate , 98% , 1795-48-8
CAS NO.：1795-48-8
Empirical Formula: C4H7NO
Molecular Weight: 85.1
MDL number: MFCD00002037
EINECS: 217-276-5
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | <-75℃ |
| Boiling point: | 74-75 °C(lit.) |
| Density | 0.866 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 27 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Soluble), Ethyl Acetate |
| form | Oil |
| color | Colourless |
| Water Solubility | Insoluble |
| Sensitive | Moisture Sensitive |
| BRN | 969356 |
| Stability: | Hygroscopic, Light Sensitive, Moisture Sensitive, Volatile |
| CAS DataBase Reference | 1795-48-8(CAS DataBase Reference) |
| EPA Substance Registry System | Propane, 2-isocyanato- (1795-48-8) |
Description and Uses
Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mTORC2). Further, it serves as a reagent in the synthesis of O-aryl N-isopropylcarbamates. In addition to this, it is used as a derivatization reagent during the stereoisomeric analysis of secondary alcohols.
Safety
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225-H315-H317-H319-H330-H334-H335 |
| Precautionary statements | P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| Hazard Codes | F,T+,Xi |
| Risk Statements | 11-26-36/37/38-42 |
| Safety Statements | 16-23-26-36/37/39-45 |
| RIDADR | UN 2483 3/PG 1 |
| WGK Germany | 1 |
| F | 10-21 |
| TSCA | Y |
| HazardClass | 3 |
| PackingGroup | I |
| HS Code | 29291090 |
