Home Categories Chemical Reagents N-Iodosuccinimide
A4989612

N-Iodosuccinimide , 97% , 516-12-1

Synonym(s):
N-Iodosuccinimide;NIS

CAS NO.:516-12-1

Empirical Formula: C4H4INO2

Molecular Weight: 224.98

MDL number: MFCD00005512

EINECS: 208-221-6

Pack Size Price Stock Quantity
5G RMB23.20 In Stock
25G RMB59.20 In Stock
100G RMB217.60 In Stock
500g RMB951.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 202-206 °C(lit.)
Boiling point: 249.6±23.0 °C(Predicted)
Density  2,245 g/cm3
storage temp.  2-8°C
solubility  Soluble in dioxane, tetrahydrfuran and acetonitrile. Insoluble in ether and carbon tetrachloride.
form  Crystalline Powder
pka -2.57±0.20(Predicted)
color  White-yellow to brown
Water Solubility  decomposes
Sensitive  Moisture Sensitive
Merck  14,5045
BRN  113917
Stability: Moisture Sensitive
InChIKey LQZMLBORDGWNPD-UHFFFAOYSA-N
CAS DataBase Reference 516-12-1(CAS DataBase Reference)

Description and Uses

N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. It is also used to hydrolyze thioglycosides to 1-hydroxyglycosides with triluoroacetic acid. It is involved in the preparation of iodobenzene from 1,6-diynes. Further, it acts as an iodinating agent in chemical synthesis.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H315-H317-H319-H341-H410
Precautionary statements  P201-P273-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  WN2817000
8-9
Hazard Note  Harmful/Keep Cold/Moisture Sensitive
TSCA  No
HazardClass  IRRITANT
HS Code  29251995

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