Iodoacetamide , 98% , 144-48-9

Synonym(s):
α-Iodoacetamide - CAS 144-48-9 - Calbiochem;2-Iodoacetamide

CAS NO.：144-48-9

Empirical Formula: C2H4INO

Molecular Weight: 184.96

MDL number: MFCD00008028

EINECS: 205-630-1

PRODUCT Properties

• Melting point: 92-95 °C(lit.)
• Boiling point: 297.1±23.0 °C(Predicted)
• Density: 2.1103 (estimate)
• storage temp.: 2-8°C
• solubility: Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.
• form: crystalline
• pka: 15.16±0.40(Predicted)
• color: White to pale yellow or beige
• Water Solubility: H2O: 0.5M at 20°C, clear, colorless
• Sensitive: Light Sensitive
• BRN: 1739080
• Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, reducing agents, acids.
• InChIKey: PGLTVOMIXTUURA-UHFFFAOYSA-N
• CAS DataBase Reference: 144-48-9(CAS DataBase Reference)
• NIST Chemistry Reference: Alpha-iodo acetamide(144-48-9)
• EPA Substance Registry System: 2-Iodoacetamide (144-48-9)

Description and Uses

2-Iodoacetamide is an alkylating reagent for cysteine residues in peptide sequencing. Its actions are similar to those of iodoacetate. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301-H317-H334-H413
• Precautionary statements: P261-P264-P273-P280-P301+P310-P302+P352
• Hazard Codes: T
• Risk Statements: 25-42/43-43-36/37/38-53
• Safety Statements: 22-36/37-45-37/39-26-24
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: AC4200000
• F: 8-10-21
• TSCA: T
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29241900