Home Categories Pharmaceutical intermediates 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine
A4920112

2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine , 98% , 99368-66-8

CAS NO.:99368-66-8

Empirical Formula: C6H3F3N2O3

Molecular Weight: 208.09

MDL number: MFCD00276983

Pack Size Price Stock Quantity
1G RMB85.60 In Stock
5G RMB261.60 In Stock
10g RMB398.40 In Stock
25G RMB860.00 In Stock
100g RMB2154.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 158°C
Boiling point: 255.2±40.0 °C(Predicted)
Density  1.61±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
pka 5.71±0.10(Predicted)
form  solid
color  Yellow
InChI InChI=1S/C6H3F3N2O3/c7-6(8,9)4-1-3(11(13)14)2-10-5(4)12/h1-2H,(H,10,12)
InChIKey BHUILUYFGJBXHQ-UHFFFAOYSA-N
SMILES C1(=O)NC=C([N+]([O-])=O)C=C1C(F)(F)F
LogP 0.41 at 25℃
CAS DataBase Reference 99368-66-8(CAS DataBase Reference)

Description and Uses

2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is a class of aromatic heterocyclic compounds that can be used as intermediates for Apalutamide, which is an androgen receptor inhibitor used in the treatment of prostate cancer.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
Hazard Note  Irritant
HS Code  2933399990

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