Home Categories Pharmaceutical intermediates Hydroquinidine-2,5-diphenyl-4,6-pyri-midinediyl diether
A4774912

Hydroquinidine-2,5-diphenyl-4,6-pyri-midinediyl diether , 97% , 149725-81-5

Synonym(s):
Hydroquinidine-2,5-diphenyl-4,6-pyrimidinediyl diether

CAS NO.:149725-81-5

Empirical Formula: C56H60N6O4

Molecular Weight: 881.11

MDL number: MFCD00198108

Pack Size Price Stock Quantity
250mg RMB157.60 In Stock
1G RMB509.60 In Stock
5g RMB1917.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 247-250 °C(lit.)
Density  1.29±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
pka 9.50±0.70(Predicted)
optical activity [α]20/D 390°, c = 1.2 in methanol

Description and Uses

(DHQD)2Pyr may be used:

  • To catalyze the enantioselective allylic amination of alkylidene cyanoacetates with dialkyl azodicarboxylates.
  • To prepare 10(R),11-Dihydroxydihydroquinine and 10(S),11-dihydroxydihydroquinine via the Sharpless catalytic asymmetric dihydroxylation.
  • In the total synthesis of okadaic acid, a protein phosphatase inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

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