A4760412
Hoveyda-Grubbs Catalyst 2nd Generation , ≥97% , 301224-40-8
Synonym(s):
(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium;Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](2-isopropoxyphenylmethylene)ruthenium(II);Grubbs Catalyst C627;Hoveyda-Grubbs Catalyst 2nd Generation;Hoveyda-Grubbs Catalyst M72 (C627)
CAS NO.：301224-40-8
Empirical Formula: C31H37Cl2N2ORu
Molecular Weight: 625.62
MDL number: MFCD03701614
EINECS: 608-446-3
| Pack Size | Price | Stock | Quantity |
| 100MG | RMB86.40 | In Stock |
|
| 500MG | RMB375.20 | In Stock |
|
| 2.5g | RMB1759.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 216-220 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Green to Very Dark Green |
| Stability: | Hygroscopic |
| InChIKey | ZRPFJAPZDXQHSM-UHFFFAOYSA-L |
Description and Uses
It′s a phosphine free version of Grubbs 2nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.
It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314-H227 |
| Precautionary statements | P501-P210-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405 |
| WGK Germany | 3 |
