Home Categories Biochemical Engineering 4-Hydroxy-D-phenylglycine
A4725212

4-Hydroxy-D-phenylglycine , 99% , 22818-40-2

Synonym(s):
(2R)-2-Amino-2-(4-hydroxyphenyl)acetic acid;4-Hydroxy-D-phenylglycine;Cefadroxyl impurity A

CAS NO.:22818-40-2

Empirical Formula: C8H9NO3

Molecular Weight: 167.16

MDL number: MFCD00004262

EINECS: 245-247-7

Pack Size Price Stock Quantity
5G RMB37.60 In Stock
25G RMB57.60 In Stock
100G RMB120.00 In Stock
500G RMB388.00 In Stock
2.5kg RMB1609.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 240 °C (dec.)(lit.)
alpha  -156 º (c=1, 1 N HCl)
Boiling point: 295.73°C (rough estimate)
Density  1.396
vapor pressure  0Pa at 25℃
refractive index  -158 ° (C=1, 1mol/L HCl)
storage temp.  2-8°C
solubility  5g/l
form  Liquid
pka 2.15±0.10(Predicted)
color  Clear colorless to yellow
optical activity [α]23/D 158±3°, c = 1 in 1 M HCl
Water Solubility  5 g/L (20 ºC)
BRN  2210998
LogP -2.25
CAS DataBase Reference 22818-40-2(CAS DataBase Reference)
EPA Substance Registry System Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.R)- (22818-40-2)

Description and Uses

d-(p-Hydroxyphenyl)glycine (d-HPG) is widely used in large amounts as an important intermediate for the synthesis of amoxicillin and several other semisynthetic β-lactam antibiotics.

4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) is an compound used mainly for the synthetic preparation of β-lactam antibiotics.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
TSCA  Yes
HS Code  29225000

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