A4711012
L-Histidine , EP, USP, non -animal source, for cell culture , 71-00-1
Synonym(s):
HIS;(S)-2-Amino-3-(4-imidazolyl)propionic acid;AKR1B11;Aldo-keto reductase family member B10;ALDRLn
CAS NO.：71-00-1
Empirical Formula: C6H9N3O2
Molecular Weight: 155.15
MDL number: MFCD00064315
EINECS: 200-745-3
| Pack Size | Price | Stock | Quantity |
| 25G | RMB143.20 | In Stock |
|
| 100G | RMB399.20 | In Stock |
|
| 1KG | RMB3120.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 282 °C (dec.)(lit.) |
| alpha | 12.4 º (c=11,6N HCl) |
| Boiling point: | 278.95°C (rough estimate) |
| Density | 1.3092 (rough estimate) |
| FEMA | 3694 | L-HISTIDINE |
| refractive index | 13 ° (C=11, 6mol/L HCl) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | 1.8(at 25℃) |
| color | White to off-white or pale yellow |
| PH | 7.0-8.0 (25℃, 0.1M in H2O) |
| PH Range | 7 - 8 at 15.5 g/l at 25 °C |
| Odor | odorless |
| Odor Type | odorless |
| optical activity | [α]20/D 39±1°, c = 2% in H2O |
| Water Solubility | 41.6 g/L (25 ºC) |
| λmax | λ: 260 nm Amax: 0.05 λ: 280 nm Amax: 0.05 |
| JECFA Number | 1431 |
| Merck | 14,4720 |
| BRN | 4673585 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | HNDVDQJCIGZPNO-YFKPBYRVSA-N |
| LogP | -1.27 |
| CAS DataBase Reference | 71-00-1(CAS DataBase Reference) |
| NIST Chemistry Reference | L-Histidine(71-00-1) |
| EPA Substance Registry System | L-Histidine (71-00-1) |
Description and Uses
White, odorless crystals or crystalline powder having a slightly bitter taste. It is soluble in water, very slightly soluble in alcohol, and insoluble in ether. It melts with decomposition between about 277° and 288°C.
L-Histidine acts as a precursor to histamine and a component of carnosine. It is also used in medicine, feed additive, biochemical research, dietary supplement. It is used in a nutrition enhancer, is the amino acid fluid infusion. It can be used in the treatment of gastric ulcer.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 24/25-36/37-26-22 |
| WGK Germany | 2 |
| RTECS | MS3070000 |
| F | 10-23 |
| TSCA | Yes |
| HS Code | 29332990 |
| Hazardous Substances Data | 71-00-1(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 5110 mg/kg |
