Gatifloxacin , ≥98% , 112811-59-3
Synonym(s):
(±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid sesquihydrate;Gatifloxacin sesquihydrate
CAS NO.：112811-59-3
Empirical Formula: C19H22FN3O4
Molecular Weight: 375.39
MDL number: MFCD00895399
EINECS: 664-293-2
| Pack Size | Price | Stock | Quantity |
| 1G | RMB319.20 | In Stock |
|
| 5G | RMB1119.20 | In Stock |
|
| 10g | RMB1919.20 | In Stock |
|
| 25g | RMB3919.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 162°C |
| Boiling point: | 607.8±55.0 °C(Predicted) |
| Density | 1.386±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly, Heated), Methanol (Slightly, Heated) |
| pka | 6.43±0.50(Predicted) |
| form | White to yellow crystalline powder. |
| color | White to Off-White |
| InChI | InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26) |
| InChIKey | XUBOMFCQGDBHNK-UHFFFAOYSA-N |
| SMILES | N1(C2CC2)C2=C(C=C(F)C(N3CCNC(C)C3)=C2OC)C(=O)C(C(O)=O)=C1 |
| CAS DataBase Reference | 112811-59-3(CAS DataBase Reference) |
Description and Uses
Gatifloxacin belongs to a class of drugs known as quinolone antibiotics and is used to treat acute sinus, lung, or urinary tract infections and sexually transmitted bacterial infection.This drug may be taken orally, in tablet form, or by injection.Common side effects associated with gatifloxacin include nausea, vaginitis(irritation or inflammation of the vagina)，diarrhea, headache, dizziness, and irregular heart beats. In general, gatifloxacin is used in people who are unresponsive to other AOM therapies.
In one study, gatifloxacin was compared with amoxicillin/clavulanate in the treatment of recurrent otitis media (OM) and AOM in treatment failures in children.Three hundred fifty-four infants and children with recurrent OM or AOM failure received gatifloxacin or amoxicillin/clavulanate.Results showed that both drugs were well tolerated; the most common side effect was diarrhea.Researchers concluded that treatment with gatifloxacin once daily was as effective as amoxicillin/clavulanate twice daily.In other medical literature, gatifloxacin has been noted as a third-line treatment option in AOM.
An antibacterial.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36/37 |
| HS Code | 29335990 |
