(-)-trans-Caryophyllene , ≥98% , 87-44-5

Synonym(s):
β-Caryophyllene;(−)-trans-Caryophyllene;trans-(1R,9S)-8-Methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene

CAS NO.：87-44-5

Empirical Formula: C15H24

Molecular Weight: 204.35

MDL number: MFCD00075925

EINECS: 201-746-1

PRODUCT Properties

• Melting point: <25℃
• alpha: D -8 to -9° (chloroform)
• Boiling point: 129-130 °C/14 mmHg (lit.)
• Density: 0.901 g/mL at 25 °C (lit.)
• vapor pressure: 6Pa at 20℃
• FEMA: 2252 | BETA-CARYOPHYLLENE
• refractive index: n20/D 1.5(lit.)
• Flash point: 205 °F
• storage temp.: -20°C
• solubility: Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
• form: Liquid
• color: Colourless
• Specific Gravity: 0.90
• Odor: at 100.00 %. sweet woody spice clove dry
• Odor Type: spicy
• optical activity: [α]23/D 7.5°, neat
• Water Solubility: 88μg/L at 20℃
• JECFA Number: 1324
• Merck: 14,1875
• BRN: 2044564
• Stability: Light Sensitive
• LogP: 6.23 at 25℃

Description and Uses

β-Caryophyllene is a sesquiterpene that has been found in plants, including C. sativa, C. indica, and hemp, and has diverse biological activities, including lipid metabolic, antioxidant, anti-neuroinflammatory, anti-proliferative, and antinociceptive properties.

β-Caryophyllene is notable for having a cyclobutane ring, a rarity in nature. β-Caryophyllene is one of the chemical compounds that contributes to the spiciness of black pepper. β-Caryophyllene was shown to selectively bind to the cannabinoid receptor type-2 (CB2) and to exert significant cannabimimetic antiinflammatory effects in mice.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H304-H317
• Precautionary statements: P261-P272-P280-P301+P310-P302+P352-P331
• Risk Statements: 36/37/38
• Safety Statements: 26-36-24/25
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• RTECS: DT8400000
• HS Code: 29021990