Gastrodin , Analysis of standard products, ≥98% , 62499-27-8
CAS NO.：62499-27-8
Empirical Formula: C13H18O7
Molecular Weight: 286.28
MDL number: MFCD00272169
EINECS: 683-202-7
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB65.60 | In Stock |
|
| 200mg | RMB615.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 169-170° |
| alpha | D20 -17.5° (c = 1 in pyridine) |
| Boiling point: | 563.2±50.0 °C(Predicted) |
| Density | 1.504±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Solid |
| pka | 9.10(at 25℃) |
| color | White to Off-White |
| λmax | 272nm(MeOH)(lit.) |
| Merck | 14,4375 |
| InChI | InChI=1/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/s3 |
| InChIKey | PUQSUZTXKPLAPR-SYDLEIBONA-N |
| SMILES | [C@@H]1([C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)OC1C=CC(CO)=CC=1 |&1:0,1,3,4,6,r| |
| LogP | -1.939 (est) |
Description and Uses
Gastrodin is extracted from the dry root of the orchid plant, Gastrodia elata. The source of raw materials is Yunnan Province. Traditional Chinese medicine Gastrodia elata (Gastrodia elata Bl.) is also known as Chi Jian, Ding Feng Cao, Shui Yang Yu, and so on, belonging to special symbiosis perennial herb of Orchidaceae and Armillaria mellea. The medicinal part is its tubers. It has sweet flavor and liver channel tropism and is neutral in nature. Traditional Chinese medicine believes that its main functions are to expel wind and relieve convulsion, calm the liver and suppress liver-yang, and expel wind evil and channel. There are 23 chemical ingredients extracted from Gastrodia elata, including gastrodin, gastrodia glycosides, vanilla alcohol, vanilla aldehyde, beta steroid valley alcohol, p-hydroxybenzoic acid, carrot glycosides, and so on, among which the highest content of single active ingredient is Gastrodia glycosides, namely, gastrodin
Gastrodin up regulates heme oxygenase-1 expression through activation of p38 MAPK/Nrf2 signaling pathway thus protecting the SH-SY5Y cells from MPP+-induced oxidative cell death.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| RTECS | LZ5776885 |
| HS Code | 29329990 |
