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A4623312

Gastrodin , Analysis of standard products, ≥98% , 62499-27-8

CAS NO.:62499-27-8

Empirical Formula: C13H18O7

Molecular Weight: 286.28

MDL number: MFCD00272169

EINECS: 683-202-7

Pack Size Price Stock Quantity
20MG RMB65.60 In Stock
200mg RMB615.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 169-170°
alpha  D20 -17.5° (c = 1 in pyridine)
Boiling point: 563.2±50.0 °C(Predicted)
Density  1.504±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Sonicated)
form  Solid
pka 9.10(at 25℃)
color  White to Off-White
λmax 272nm(MeOH)(lit.)
Merck  14,4375
InChI InChI=1/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/s3
InChIKey PUQSUZTXKPLAPR-SYDLEIBONA-N
SMILES [C@@H]1([C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)OC1C=CC(CO)=CC=1 |&1:0,1,3,4,6,r|
LogP -1.939 (est)
CAS DataBase Reference 62499-27-8(CAS DataBase Reference)

Description and Uses

Gastrodin is extracted from the dry root of the orchid plant, Gastrodia elata. The source of raw materials is Yunnan Province. Traditional Chinese medicine Gastrodia elata (Gastrodia elata Bl.) is also known as Chi Jian, Ding Feng Cao, Shui Yang Yu, and so on, belonging to special symbiosis perennial herb of Orchidaceae and Armillaria mellea. The medicinal part is its tubers. It has sweet flavor and liver channel tropism and is neutral in nature. Traditional Chinese medicine believes that its main functions are to expel wind and relieve convulsion, calm the liver and suppress liver-yang, and expel wind evil and channel. There are 23 chemical ingredients extracted from Gastrodia elata, including gastrodin, gastrodia glycosides, vanilla alcohol, vanilla aldehyde, beta steroid valley alcohol, p-hydroxybenzoic acid, carrot glycosides, and so on, among which the highest content of single active ingredient is Gastrodia glycosides, namely, gastrodin

Gastrodin up regulates heme oxygenase-1 expression through activation of p38 MAPK/Nrf2 signaling pathway thus protecting the SH-SY5Y cells from MPP+-induced oxidative cell death.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
RTECS  LZ5776885
HS Code  29329990

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