Glycine ethyl ester hydrochloride , 99% , 623-33-6

Synonym(s):
Ethyl glycinate hydrochloride;GEE

CAS NO.：623-33-6

Empirical Formula: C4H10ClNO2

Molecular Weight: 139.58

MDL number: MFCD00012871

EINECS: 210-787-4

PRODUCT Properties

• Melting point: 145-146 °C(lit.)
• Density: 1.371 g/cm3
• storage temp.: 2-8°C
• solubility: >1000 g/L (20 °C)
• form: Crystalline Powder
• pka: pK1:7.66(＋1) (25°C)
• color: White
• Odor: Odorless
• PH: 2.9 (10g/l, H2O, 20℃)
• Water Solubility: >1000 g/L (20 ºC)
• Sensitive: Hygroscopic
• BRN: 3594034
• InChIKey: TXTWXQXDMWILOF-UHFFFAOYSA-N
• CAS DataBase Reference: 623-33-6(CAS DataBase Reference)
• EPA Substance Registry System: Glycine, ethyl ester, hydrochloride (623-33-6)

Description and Uses

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H318
• Precautionary statements: P280-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 41-36/37/38
• Safety Statements: 26-39-24/25-37/39
• WGK Germany: 3
• RTECS: MC0525000
• TSCA: Yes
• HS Code: 29224995