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A4408112

Flutamide , >98.0%(GC) , 13311-84-7

Synonym(s):
2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide;Flutamide

CAS NO.:13311-84-7

Empirical Formula: C11H11F3N2O3

Molecular Weight: 276.21

MDL number: MFCD00072009

EINECS: 236-341-9

Pack Size Price Stock Quantity
5G RMB85.60 In Stock
25G RMB342.40 In Stock
100G RMB1002.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 112 °C
Boiling point: 400.3±45.0 °C(Predicted)
Density  1.3649 (estimate)
storage temp.  2-8°C
solubility  Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent).
pka 13.12±0.70(Predicted)
form  Solid
color  Pale Yellow to Light Yellow
Merck  14,4208
InChI InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChIKey MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)(=O)C(C)C
CAS DataBase Reference 13311-84-7(CAS DataBase Reference)
EPA Substance Registry System Flutamide (13311-84-7)

Description and Uses

Flutamide is an orally active, non-steroidal antiandrogen indicated for the treatment of prostatic cancer in both castrates and noncastrates.

Besides prostate cancer, flutamide has also been tested and/or used off-label in other hyperandrogenism-related disorders like benign prostatic hyperplasia, acne vulgaris, and hirsutism syndrome. Due to its teratogenic potential, flutamide is restricted for premenopausal women and used only in combination with effective contraception.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H351-H361-H373-H411
Precautionary statements  P202-P260-P264-P273-P301+P312-P308+P313
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-63-36/37/38
Safety Statements  22-36-36/37/39-27-26
WGK Germany  3
RTECS  UG5700000
HS Code  29242990

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