A4382412
4-Fluorophenylmagnesium bromide solution , 1.0MinMeTHF , 352-13-6
CAS NO.：352-13-6
Empirical Formula: C6H4BrFMg
Molecular Weight: 199.31
MDL number: MFCD00009667
EINECS: 627-087-3
| Pack Size | Price | Stock | Quantity |
| 100ML | RMB271.20 | In Stock |
|
| 250ml | RMB583.20 | In Stock |
|
| 500ML | RMB1039.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 5 °C |
| Boiling point: | 66°C |
| Density | 1.043 g/mL at 25 °C |
| Flash point: | −40 °F |
| storage temp. | Flammables + water-Freezer (-20°C)e area |
| form | Solution |
| color | Clear yellow to red-brown |
| Water Solubility | It reacts violently with water. |
| Sensitive | Air & Moisture Sensitive |
| BRN | 636802 |
| InChIKey | QYBFFRXNNFXREA-UHFFFAOYSA-M |
Description and Uses
4-Fluorophenylmagnesium bromide solution (Grignard reagent) can be used as a reagent in the synthesis of:
- Useful key intermediate in the synthesis of paroxetine.
- Arylsulfides via cross-coupling reaction with thiols.
- 4-Arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as androgen receptor antagonists.
- Grignard intermediate for preparing aprepitant.
Safety
| Symbol(GHS) |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225-H302-H314-H335-H351-H336-H318-H371-H372 |
| Precautionary statements | P233-P240-P241+P242+P243-P264-P270-P271-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P311-P403+P233-P405-P501-P260h-P303+P361+P353-P501a-P210-P260-P280-P305+P351+P338-P370+P378-P403+P235-P261-P310 |
| Hazard Codes | F+,C,F |
| Risk Statements | 12-14-22-34-66-67-11-40-37-19 |
| Safety Statements | 16-26-36/37/39-43-45-7/8-33-8-7 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 1 |
| F | 10-21 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29319090 |
