Fluvastatin Sodium , ≥98% , 93957-55-2
Synonym(s):
(±)-(3Rʹ,5Sʹ,6E)-7-(3-(4-Fluorophenyl)-1-isopropylindol-2-yl)-3,5-dihydroxy-6-heptenoate, sodium;(±)-(3Rʹ,5Sʹ,6E)-7-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxy-6-heptenoate, sodium;(±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt hydrate;(3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt;InSolution
CAS NO.:93957-55-2
Empirical Formula: C24H25FNNaO4
Molecular Weight: 433.45
MDL number: MFCD00929076
EINECS: 1308068-626-2
Pack Size | Price | Stock | Quantity |
50MG | RMB75.20 | In Stock |
|
250MG | RMB175.20 | In Stock |
|
1G | RMB439.20 | In Stock |
|
5G | RMB1399.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 194-197°C |
storage temp. | 2-8°C |
solubility | H2O: ≥9mg/mL |
form | powder |
color | white to tan |
Merck | 14,4218 |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
InChIKey | ZGGHKIMDNBDHJB-RPQBTBOMSA-M |
Description and Uses
Fluvastatin sodium is the fourth HMG-CoA reductase inhibitor to reach the market as a dietary adjunct for lowing total and low-density lipoprotein (LDL) cholesterol. Fluvastatin sodium is the first totally synthetic inhibitor of its class and has more potent effects on reducing serum total and LDL cholesterol and serum triglyceride levels than compactin or lovastatin. Moreover, fluvastatin exhibits a unique set of pharmacological properties including a biopharmaceutical profile most consistent with hepatoselectivity. It has been reported to be well tolerated and to exhibit a safety profile superior to other agents of its class. The main mechanism by which HMG-CoA reductase inhibitors lower plasma cholesterol has been suggested to be up-regulation of hepatocellular LDL-receptor expression and enhancement of receptor-mediated clearance and catabolism of LDL cholesterol.
Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 3 |
RTECS | MJ9675050 |
HS Code | 2933995300 |