Furosemide , ≥98% , 54-31-9

Synonym(s):
Furosemide;STING;FUR;MITA;4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid

CAS NO.：54-31-9

Empirical Formula: C12H11ClN2O5S

Molecular Weight: 330.74

MDL number: MFCD00010549

EINECS: 200-203-6

PRODUCT Properties

• Melting point: 220 °C (dec.) (lit.)
• Boiling point: 582.1±60.0 °C(Predicted)
• Density: 1.606
• refractive index: 1.6580 (estimate)
• Flash point: 11 °C
• storage temp.: 2-8°C
• solubility: Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
• pka: pKa 3.8 (Uncertain)
• form: powder
• color: White to Off-White
• Water Solubility: Soluble in acetone, DMF or methanol. Slightly soluble in water
• Merck: 14,4309
• BCS Class: 2 (CLogP), 4 (LogP)
• Stability: Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
• InChIKey: ZZUFCTLCJUWOSV-UHFFFAOYSA-N
• CAS DataBase Reference: 54-31-9(CAS DataBase Reference)
• IARC: 3 (Vol. 50) 1990
• EPA Substance Registry System: Furosemide (54-31-9)

Description and Uses

Furosemide (Item No. 26298) is an analytical reference standard categorized as a diuretic. Formulations containing diuretics, including furosemide, have been misused in sports for weight reduction and as masking agents in humans and to prevent exercise-induced pulmonary hemorrhage in racehorses. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .

An inhibitor of NKCC and a GABAA receptor antagonist.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360FD
• Precautionary statements: P202-P264-P270-P280-P301+P312-P308+P313
• Hazard Codes: T,F,Xi
• Risk Statements: 61-39/23/24/25-23/24/25-11-36/37/38
• Safety Statements: 7-16-36/37-45-53-36/37/39-22-36-26
• RIDADR: UN 1230 3/PG 2
• WGK Germany: 3
• RTECS: CB2625000
• HS Code: 2935904000
• Hazardous Substances Data: 54-31-9(Hazardous Substances Data)
• Toxicity: LD50 orally in female, male rats: 2600, 2820 mg/kg (Goldenthal)