Fmoc-D-Tyr(tBu)-OH , 98% , 118488-18-9

Synonym(s):
Fmoc-O-tert-butyl-D-tyrosine;Fmoc-D-Tyr(tBu)-OH;N-α-Fmoc-O-t.-butyl-D-tyrosine

CAS NO.：118488-18-9

Empirical Formula: C28H29NO5

Molecular Weight: 459.53

MDL number: MFCD00065684

PRODUCT Properties

• Melting point: 150.0 to 154.0 °C
• Boiling point: 658.2±55.0 °C(Predicted)
• Density: 1.218±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: powder to crystal
• pka: 2.97±0.10(Predicted)
• color: White to Almost white
• Water Solubility: Soluble in 1 mmole in 2 ml dimethylformamide (Clearly soluble). Slightly soluble in water.
• BRN: 6691868
• InChIKey: JAUKCFULLJFBFN-RUZDIDTESA-N
• SMILES: C(O)(=O)[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

Description and Uses

Fmoc-D-Tyr(tBu)-OH is a precursor for the synthesis of thyroxine, dopa and adrenaline in medicine. It is directly involved in the synthesis of neurotransmitters such as dopamine, norepinephrine and epinephrine, and in the control of neurotransmitter levels, and is involved in the synthesis of hormones of thyroid, pituitary and other glands. In the feed industry, Fmoc-D-Tyr(tBu)-OH can be used as a feed additive in the feed of chicks. On the one hand, it minimizes the amount of phenylalanine converted to tyrosine to maintain the balance of amino acids in the growth of livestock and poultry. On the other hand, it can avoid chicks and piglets to lose weight due to insufficient tyrosine in the body and the destruction of thyroid and adrenal hormones.

N-Fmoc-O-tert-butyl-D-tyrosine is potentially useful for proteomics studies and solid phase peptide synthesis techniques.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H413-H317
• Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• HS Code: 29224999