2-Fluoroadenine , 98% , 700-49-2
Synonym(s):
2-Fluoro-7(9)H-purin-6-ylamine
CAS NO.：700-49-2
Empirical Formula: C5H4FN5
Molecular Weight: 153.12
MDL number: MFCD01632749
EINECS: 624-159-6
| Pack Size | Price | Stock | Quantity |
| 250MG | RMB69.60 | In Stock |
|
| 1G | RMB119.20 | In Stock |
|
| 5g | RMB479.20 | In Stock |
|
| 25g | RMB2159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >350 °C(lit.) |
| Boiling point: | 239.6±50.0 °C(Predicted) |
| Density | 2.05±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 6.84±0.20(Predicted) |
| color | White to Light Yellow |
| CAS DataBase Reference | 700-49-2(CAS DataBase Reference) |
Description and Uses
2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy. It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. It is also cytotoxic to CEM human leukemia cells with an IC50 value of 0.15 μM.
2-Fluoroadenine is a fluorinated heterocyclic 2-ring compound. It is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. 2-Fluoroadenine has been used as an intermediate for antineoplastic drugs such as fludarabine. fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | AU6264700 |
| Hazard Note | Irritant |
| HazardClass | IRRITANT, IRRITANT-HARMFUL |
| HS Code | 29335990 |
