Fmoc-Pen(Trt)-OH , 97% , 201531-88-6
Synonym(s):
Fmoc-α, α-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine;Fmoc-β,β-dimethyl-Cys(Trt)-OH;Fmoc-S-trityl-L -penicillamine;Fmoc-Pen(Trt)-OH
Pack Size | Price | Stock | Quantity |
500MG | RMB319.20 | In Stock |
|
1G | RMB492.00 | In Stock |
|
5g | RMB1990.40 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 768.8±60.0 °C(Predicted) |
alpha | 33 º (c=1 in methanol) |
Density | 1.242±0.06 g/cm3(Predicted) |
storage temp. | Store at -15°C to -25°C. |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Powder |
pka | 3.70±0.10(Predicted) |
optical activity | [α]/D +33±2°, c = 1 in methanol |
InChIKey | XSGMGAINOILNJR-PGUFJCEWSA-N |
SMILES | C(O)(=O)[C@H](C(SC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
CAS DataBase Reference | 201531-88-6(CAS DataBase Reference) |
Description and Uses
Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.
Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity.
Safety
Hazard statements | H413 |
WGK Germany | 3 |
HS Code | 2930 90 16 |
HazardClass | IRRITANT |