Fmoc-lle-OH , 99% , 71989-23-6

Synonym(s):
N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine;Fmoc-L-isoleucine;Fmoc-Ile-OH;N-α-Fmoc-L-isoleucine

CAS NO.：71989-23-6

Empirical Formula: C21H23NO4

Molecular Weight: 353.41

MDL number: MFCD00037125

EINECS: 276-255-9

PRODUCT Properties

• Melting point: 145-147 °C(lit.)
• alpha: -12 º (c=1,DMF)
• Boiling point: 486.83°C (rough estimate)
• Density: 1.2107 (rough estimate)
• refractive index: -12 ° (C=1, DMF)
• storage temp.: 2-8°C
• solubility: Soluble in methanol (very faint turbidity).
• form: Fine Crystalline Powder
• pka: 3.92±0.22(Predicted)
• color: White
• optical activity: [α]20/D 12±1°, c = 1% in DMF
• BRN: 4716717
• InChI: InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1
• InChIKey: QXVFEIPAZSXRGM-DJJJIMSYSA-N
• SMILES: C(O)(=O)[C@H]([C@@H](C)CC)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
• CAS DataBase Reference: 71989-23-6(CAS DataBase Reference)

Description and Uses

Fmoc-Ile-OH is an isoleucine derivative. It is white fine crystalline powder and belong to Fmoc materials. Fmoc-Leu-OH forms flower-like morphology at both low and high concentration under room temperature which changes to small tube-like structure on heating^[1].

N-Fmoc-L-isoleucine is an unnatural amino acid used for peptidomimetics. It is also used as a pharmaceutical intermediate.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36/37/39-27-26
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 2924 29 70