7-Ethoxycoumarin , >97.0%(HPLC) , 31005-02-4
Synonym(s):
7-Ethoxy-1-benzopyran-2-one
CAS NO.：31005-02-4
Empirical Formula: C11H10O3
Molecular Weight: 190.2
MDL number: MFCD00006877
EINECS: 250-429-4
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB47.20 | In Stock |
|
| 500mg | RMB159.20 | In Stock |
|
| 5G | RMB479.20 | In Stock |
|
| 25G | RMB1839.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 88-90 °C (lit.) |
| Boiling point: | 265.69°C (rough estimate) |
| Density | 1.1803 (rough estimate) |
| refractive index | 1.4260 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Brown |
| Water Solubility | Soluble in hot methanol (very faint turbidity), 95% ethanol (50 mg/ml), DMF, and DMSO. Insoluble in water. |
| BRN | 146200 |
| LogP | 2.310 (est) |
| CAS DataBase Reference | 31005-02-4(CAS DataBase Reference) |
Description and Uses
7-Ethoxycoumarin is oneof the general substrates for liver cytochrome P450 enzymes, and it is known that CYP1A1,1A2, and 2B1, drug inducedtypes (b-naphthoflavone, isosafrole, and phenobarbital,re-spectively, in rat liver) are mainly responsible for the ECDE activity in the liver.
7-Ethoxycoumarin is commonly used for metabolism studies, including hepatocyte studies, liver perfusion techniques and cytochrome P450 studies.
7-Ethoxycoumarin has been used to study the functional activity of recombinant P450. ) It has also been used as an internal standard for in vitro S-warfarin 7-hydroxylation and high performance liquid chromatography (HPLC) analysis.
Safety
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 8 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29329990 |
