Eflornithine hydrochloride hydrate , >98.0%(T) , 96020-91-6

Synonym(s):
DFMO, Eflornithine, RMI-71782;DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

CAS NO.：96020-91-6

Empirical Formula: C6H15ClF2N2O3

Molecular Weight: 236.64

MDL number: MFCD00242734

PRODUCT Properties

• Melting point: >210°C (dec.)
• storage temp.: Inert atmosphere,2-8°C
• solubility: Soluble in Water (up to 25 mg/ml).
• form: White powder
• color: White
• Merck: 14,3522
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
• CAS DataBase Reference: 96020-91-6

Description and Uses

Difluoromethylornithine HCl (96020-91-6) is a selective inhibitor of ornithine decarboxylase.1?Induces apoptosis in a variety of cells.2?Difluoromethylornithine HCl displays cancer chemopreventive activity.3?Cell permeable. Active in vivo.

Eflornithine hydrochloride hydrate is irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• RTECS: RM2981900
• HS Code: 2922493800