Ethyl carbazate , ≥99.0% , 4114-31-2

Synonym(s):
Hydrazinocarboxylic acid ethyl ester

CAS NO.：4114-31-2

Empirical Formula: C3H8N2O2

Molecular Weight: 104.11

MDL number: MFCD00007595

EINECS: 223-903-3

PRODUCT Properties

• Melting point: 44-47 °C (lit.)
• Boiling point: 108-110 °C/22 mmHg (lit.)
• Density: 1.2719 (rough estimate)
• refractive index: 1.4715 (estimate)
• Flash point: 187 °F
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• form: Powder
• pka: 10.72±0.20(Predicted)
• color: White to cream
• Water Solubility: Very soluble in water.
• Sensitive: Moisture Sensitive
• BRN: 878265
• InChIKey: VYSYZMNJHYOXGN-UHFFFAOYSA-N

Description and Uses

Prepare 4-phenylurazole from ethyl carbazate and then oxidize the urazole with gaseous dinitrogen tetroxide to yield 4-phenyl-1,2,4-tri- azoline-3,5-dione la. Modification of the ethyl carbazate procedure in which analytically pure monoalkylhydrazine hydrochlorides were isolated in greater than 90% yield, starting from a ketone or aldehyde. Treatment of primary amines is with chloroamine or hydroxylamine-0-sulfonic acid and the condensation of a carbonyl compound with ethyl carbazate. The FeCl 3 -catalyzed reaction of ethyl carbazate (2 b) proceeded readily to give β-hydroxyester 3 b in better yield. A new one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones through cyclocondensation of ethyl carbazate with aryl nitriles catalyzed by DMAP as an efficient and basic nucleophilic catalyst is described.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,T
• Risk Statements: 36/37/38-25
• Safety Statements: 26-36-45
• RIDADR: 2811
• WGK Germany: 3
• RTECS: FE2545000
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29280090