Home Categories Chemical Reagents Ethyl trifluoromethanesulfonate
A3992912

Ethyl trifluoromethanesulfonate , forGCderivatization,≥99.0% , 425-75-2

CAS NO.:425-75-2

Empirical Formula: C3H5F3O3S

Molecular Weight: 178.13

MDL number: MFCD00000410

EINECS: 207-037-3

Pack Size Price Stock Quantity
5ML RMB717.60 In Stock
25ml RMB3199.20 In Stock
50ml RMB5599.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 115 °C (lit.)
Density  1.374 g/mL at 25 °C (lit.)
refractive index  n20/D 1.336(lit.)
Flash point: 96 °F
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform, Methanol (Slightly)
form  Oil
color  Colourless
Specific Gravity 1.374
Water Solubility  Hydrolyzes in water.
Sensitive  Hygroscopic
BRN  1770746
Stability: Volatile
InChIKey UVECLJDRPFNRRQ-UHFFFAOYSA-N
CAS DataBase Reference 425-75-2(CAS DataBase Reference)
EPA Substance Registry System Methanesulfonic acid, trifluoro-, ethyl ester (425-75-2)

Description and Uses

Ethyl trifluoromethanesulfonate is a cationic polymerization agent used to produce polyurethane, polyacrylate, and other synthetic resins. It is an effective drug for the treatment of HIV infection and chronic bronchitis. Ethyl trifluoromethanesulfonate has been shown to inhibit the replication of HIV-1 virus at concentrations as low as 1 μM when tested in vitro. The mechanism of this drug's anti-HIV activity is unknown and may involve the inhibition of reverse transcriptase or proteases. Ethyl trifluoromethanesulfonate can be detected in vivo up to 4 hours after administration. This drug is metabolized into trifluoroacetic acid by esterases, glycosidases, and/or oxidases.

Ethyl trifluoromethanesulfonate is a powerful ethylating agent. due to the strong electron-absorbing ability of trifluoromethanesulfonyl, the reactivity is much higher than that of conventional alkylation reagents such as bichloride or alkyl sulfonate.

Safety

Symbol(GHS) 
GHS02,GHS05
Signal word  Danger
Hazard statements  H226-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  C,T,F
Risk Statements  10-34
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2920 8/PG 2
WGK Germany  2
3
Hazard Note  Highly Toxic
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29049090

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