Ethyl trifluoromethanesulfonate , 98% , 425-75-2

CAS NO.：425-75-2

Empirical Formula: C3H5F3O3S

Molecular Weight: 178.13

MDL number: MFCD00000410

EINECS: 207-037-3

PRODUCT Properties

• Boiling point: 115 °C (lit.)
• Density: 1.374 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.336(lit.)
• Flash point: 96 °F
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform, Methanol (Slightly)
• form: Oil
• color: Colourless
• Specific Gravity: 1.374
• Water Solubility: Hydrolyzes in water.
• Sensitive: Hygroscopic
• BRN: 1770746
• Stability: Volatile
• InChIKey: UVECLJDRPFNRRQ-UHFFFAOYSA-N

Description and Uses

Ethyl trifluoromethanesulfonate is a cationic polymerization agent used to produce polyurethane, polyacrylate, and other synthetic resins. It is an effective drug for the treatment of HIV infection and chronic bronchitis. Ethyl trifluoromethanesulfonate has been shown to inhibit the replication of HIV-1 virus at concentrations as low as 1 μM when tested in vitro. The mechanism of this drug's anti-HIV activity is unknown and may involve the inhibition of reverse transcriptase or proteases. Ethyl trifluoromethanesulfonate can be detected in vivo up to 4 hours after administration. This drug is metabolized into trifluoroacetic acid by esterases, glycosidases, and/or oxidases.

Ethyl trifluoromethanesulfonate is a powerful ethylating agent. due to the strong electron-absorbing ability of trifluoromethanesulfonyl, the reactivity is much higher than that of conventional alkylation reagents such as bichloride or alkyl sulfonate.

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H226-H314
• Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
• Hazard Codes: C,T,F
• Risk Statements: 10-34
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 2920 8/PG 2
• WGK Germany: 2
• F: 3
• Hazard Note: Highly Toxic
• TSCA: Yes
• HazardClass: 8
• PackingGroup: II
• HS Code: 29049090