Erythrosin B , 85% , 16423-68-0

Synonym(s):
2′,4′,5′,7′-Tetraiodofluorescein disodium salt;Acid Red 51;Erythrosin extra bluish;Iodoeosin;Solvent Red 140

CAS NO.：16423-68-0

Empirical Formula: C20H6I4Na2O5

Molecular Weight: 879.86

MDL number: MFCD00144257

EINECS: 240-474-8

PRODUCT Properties

• Melting point: 142~144℃
• Density: 0.98
• vapor pressure: 0Pa at 25℃
• Flash point: 285℃
• storage temp.: room temp
• solubility: 100g/l
• form: Fine Powder
• Colour Index: 45430
• pka: 4.1(at 25℃)
• color: Deep red to brown
• PH Range: 0(yellow)-3.6(red)
• PH: 6-7 (10g/l, H2O, 20℃)
• Water Solubility: Soluble in water
• λmax: 525nm
• Merck: 14,3693
• BRN: 1443945
• Stability: Stable. Incompatible with strong oxidizing agents.
• Biological Applications: Detecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity
• Major Application: color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy
• InChIKey: RAGZEDHHTPQLAI-UHFFFAOYSA-L
• LogP: -1.163 at 25℃

Description and Uses

FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .

Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H411
• Precautionary statements: P264-P270-P273-P301+P312-P391-P501
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: LM5950000
• HS Code: 32129000
• Toxicity: LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)