Ethyl oleate , 75.0%(GC) , 111-62-6

Synonym(s):
Ethylis oleas;Ethyloleate;Oleic acid ethyl ester

CAS NO.：111-62-6

Empirical Formula: C20H38O2

Molecular Weight: 310.51

MDL number: MFCD00009579

EINECS: 203-889-5

PRODUCT Properties

• Melting point: −32 °C(lit.)
• Boiling point: 216-218 °C15 mm Hg
• Density: 0.87 g/mL at 25 °C(lit.)
• FEMA: 2450 | ETHYL OLEATE
• refractive index: n20/D 1.451(lit.)
• Flash point: >230 °F
• storage temp.: -20°C
• solubility: chloroform: soluble10%
• form: Oily Liquid
• color: Clear
• Odor: at 100.00 %. fatty oily dairy milky waxy tallow
• Odor Type: fatty
• Sensitive: Light Sensitive
• Merck: 14,6828
• JECFA Number: 345
• BRN: 1727318
• Dielectric constant: 3.2（28℃）
• InChIKey: LVGKNOAMLMIIKO-VAWYXSNFSA-N
• LogP: 8.69

Description and Uses

Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication.
Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer. The Food and Drug Administration regulates its use as a food additive under "Food Additives Permitted for Direct Addition to Food for Human Consumption", 21CFR172.515.

Ethyl oleate is a flavoring and fragrance agent. Usually used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac). It was obtained by the hydrolysis of various animal and vegetable fats and oils.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
• Safety Statements: 23-24/25-22
• WGK Germany: 2
• RTECS: RG3715000
• F: 10-23
• TSCA: Yes
• HS Code: 29161900
• Toxicity: rabbit,LD50,skin,> 5gm/kg (5000mg/kg),Food and Chemical Toxicology. Vol. 20, Pg. 683, 1982.