Ethyl α-bromoisobutyrate , 98% , 600-00-0

Synonym(s):
Ethyl 2-bromo-2-methylpropionate

CAS NO.：600-00-0

Empirical Formula: C6H11BrO2

Molecular Weight: 195.05

MDL number: MFCD00000123

EINECS: 209-980-6

PRODUCT Properties

• Boiling point: 65-67 °C11 mm Hg(lit.)
• Density: 1.329 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.444(lit.)
• Flash point: 140 °F
• storage temp.: 2-8°C
• form: Liquid
• color: Clear colorless to light yellow
• Water Solubility: Soluble in alcohol, ether. Insoluble in water.
• BRN: 1098947
• Dielectric constant: 7.9（20℃）
• Stability: Stable. Incompatible with acids, bases, reducing agents, oxidizing agents.
• InChI: InChI=1S/C6H11BrO2/c1-4-9-5(8)6(2,3)7/h4H2,1-3H3
• InChIKey: IOLQWGVDEFWYNP-UHFFFAOYSA-N
• SMILES: C(OCC)(=O)C(Br)(C)C
• CAS DataBase Reference: 600-00-0(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-bromo-2-methyl-, ethyl ester(600-00-0)
• EPA Substance Registry System: Ethyl 2-bromoisobutyrate (600-00-0)

Description and Uses

Ethyl 2-bromoisobutyrate is an organic compound used in organic synthesis as a catalyst or starting material. The compound has a strong halogen group and can undergo multiple reactions, making it useful in various chemical reactions. One application of this compound is synthesizing cationic polymers for antibacterial peptide mimicry. These polymers showed promising antimicrobial activity against various strains of bacteria.

Ethyl 2-bromoisobutyrate is used as an Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with an ethyl end group.

Safety

• Symbol(GHS): GHS02,GHS05,GHS07
• Signal word: Danger
• Hazard statements: H226-H302-H318
• Precautionary statements: P210-P233-P240-P280-P301+P312-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-41-36/37/38
• Safety Statements: 26-39-37/39
• RIDADR: UN 1992 3/PG 3
• WGK Germany: 3
• F: 19
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• HS Code: 29159080