Diphenhydramine , ≥98.0%(GC) , 58-73-1

CAS NO.：58-73-1

Empirical Formula: C17H21NO

Molecular Weight: 255.35

MDL number: MFCD00274173

EINECS: 200-396-7

PRODUCT Properties

• Melting point: 167-172°C
• Boiling point: bp2.0 150-165°
• Density: 0.9889 (rough estimate)
• refractive index: 1.5450 to 1.5490
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Oil
• pka: pKa 9.1 (Uncertain)
• color: Oil
• Merck: 14,3309
• BCS Class: 1
• CAS DataBase Reference: 58-73-1(CAS DataBase Reference)
• NIST Chemistry Reference: Ethylamine, 2-diphenylmethoxy-n,n-dimethyl-(58-73-1)
• EPA Substance Registry System: Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl- (58-73-1)

Description and Uses

Diphenhydramine is one of the main representatives of antihistamine drugs that block H1 receptors. Besides antihistamine activity, diphenhydramine exhibits a local anesthetic effect, relaxes smooth muscle, and has sedative and soporific action.

Antihistaminic.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319-H315-H302
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
• RTECS: KR6825000
• HS Code: 2922.19.7000
• Hazardous Substances Data: 58-73-1(Hazardous Substances Data)
• Toxicity: LD50 oral in rat: 390mg/kg