Diethyl Ethylmalonate , >98.0%(GC) , 133-13-1

Synonym(s):
Diethyl ethylmalonate;Ethylmalonic acid diethyl ester

CAS NO.：133-13-1

Empirical Formula: C9H16O4

Molecular Weight: 188.22

MDL number: MFCD00009167

EINECS: 205-093-3

PRODUCT Properties

• Melting point: 0°C
• Boiling point: 75-77 °C/5 mmHg (lit.)
• Density: 1.004 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.416(lit.)
• Flash point: 191 °F
• storage temp.: Store below +30°C.
• solubility: 2.87g/l
• form: Liquid
• pka: 13.17±0.46(Predicted)
• color: Clear colorless
• PH: 4.46 at 24.3℃ and 10g/L
• Water Solubility: immiscible
• BRN: 607635
• LogP: 2.4 at 30℃ and pH7.93
• CAS DataBase Reference: 133-13-1(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, ethyl-, diethyl ester(133-13-1)
• EPA Substance Registry System: Propanedioic acid, ethyl-, diethyl ester (133-13-1)

Description and Uses

Diethyl Ethylmalonate is used in the synthesis of HIV-1 reverse transcriptase inhibitors. Also used in the preparation of Peloruside A, a novel antimitotic agent used as a potential anti-cancer agent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H227
• Precautionary statements: P210e-P280a-P370+P378a-P403+P235-P501a
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 24/25-36-26
• WGK Germany: 2
• TSCA: Yes
• HS Code: 29171990
• Toxicity: LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rat > 2000 mg/kg